• The Waiting Time Problem in a Model Hominin Population

• Mendel’s Accountant: A Biologically Realistic Forward-Time Population Genetics Program

• Using computer Simulation to Understand Mutation Accumulation Dynamics and Genetic Load

• The Next Step in Understanding Population Dynamics- Comprehensive Numerical Simulation

Biological Information – New Perspectives:

• Can Purifying Natural Selection Preserve Biological Information

• Selection Threshold Severely Constrains Capture of Beneficial Mutations

• Using Numerical Simulation to Test the “Mutation-Count” Hypothesis

• Can Synergistic Epistasis Halt Mutation Accumulation? Results from Numerical Simulation

• Computational Evolution Experiments Reveal a Net Loss of Genetic Information Despite Selection

• Information Loss: Potential for Accelerating Natural Genetic Attenuation of RNA Viruses